Clinician-prescribed therapies · Personally reviewed by your provider
MetabolismGLP-1 receptor agonist

GLP-1 weight management, prescribed personally.*

Semaglutide is a long-acting GLP-1 receptor agonist. Tides prescribes a compounded formulation with full labs, clinician-managed titration, and quarterly review. Compounded semaglutide is not FDA-approved and is not the same product as brand-name GLP-1s.

Metabolism
Semaglutide
GLP-1 receptor agonist
Tides · Clinician-Prescribed

Quick read

What it is
A long-acting GLP-1 receptor agonist that signals the brain to lower appetite and helps the pancreas release insulin in response to meals. Tides prescribes a compounded formulation via a US 503A pharmacy; compounded semaglutide is not FDA-approved and is not the same product as brand-name GLP-1s.
Primary benefit
Sustained appetite reduction and meaningful weight loss when paired with a personalized dose titration and ongoing clinical review.
Mechanism
Activates GLP-1 receptors in the brain, gut, and pancreas. The brain effect dampens hunger and slows gastric emptying; the pancreatic effect improves insulin response to meals.
Who it's for
Adults pursuing meaningful weight loss who want a clinically-supervised protocol with full lab panels and dose titration, not a hand-off prescription.
Read the full science

What it does

  • Appetite reduction that holds
    GLP-1 receptor activation in the brain dampens hunger signals and reduces food noise. Once-weekly dosing carries the effect cleanly through the full week.
  • Improved insulin response
    GLP-1 action on pancreatic beta cells improves how cleanly the body handles glucose at meals. A1C and fasting insulin both shift in measurable timeframes.
  • Steady, controlled weight loss
    Reduced calorie intake plus slower gastric emptying drives gradual, sustainable weight reduction. Paired with full labs and quarterly review so the protocol stays calibrated to you.
  • Metabolic markers move with you
    Lipids, blood pressure, and inflammatory markers tend to move in the right direction alongside weight loss. The body composition shift is a downstream effect of the metabolic reset.

How it works

Semaglutide is a long-acting GLP-1 receptor agonist. It binds the GLP-1 receptor in the brain (appetite center), the gut (slows stomach emptying so meals feel filling longer), and the pancreas (improves glucose-responsive insulin release). Tides prescribes a compounded formulation through a US 503A pharmacy, with full lab panels and clinician-managed dose titration. Compounded semaglutide is not FDA-approved and is not the same product as brand-name GLP-1s.

Clinical context

Typical dose
2.4 mg weekly
Range
0.25–2.4 mg/week
Route
Subcutaneous
Per vial
25 mg · ~73 days
Required labs
A1C, Lipid Panel, Comprehensive Metabolic Panel, Lipase

Who it's for

  • Meaningful, supervised weight loss
  • Prediabetic A1C or insulin resistance markers
  • Patients who want quarterly clinician review, not a one-time prescription
  • Body composition reset alongside training

Cautions

  • Mandatory titration: every patient starts at 1 mg/week
  • Quarterly clinical review required (every 90 days)
  • Not for personal or family history of medullary thyroid carcinoma

Pairs with

Glutathione
Supports the body’s own antioxidant systems.
Methylcobalamin
Energy and neurological support.
From $179/moLASTS ABOUT 10 WEEKS

Semaglutide compounded vial. Cycle length depends on your prescribed dose, Rachel calibrates the titration to you. Pharmacy and clinician fees included.

Start your intake
Dose ladder

Priced by dose

As Dr. Rachel advances your protocol, price and shipment step up together. Every step is priced separately so you always know what the next one costs before it happens.

0.25 mg weekly
Titration start
$179/mo
1 vial (12.5 mg), a 3-month supply. One charge of $537.
0.5 mg weekly
Titration
$179/mo
1 vial (12.5 mg), a 3-month supply. One charge of $537.
1.0 mg weekly
Titration
$199/mo
1 vial (12.5 mg), a 3-month supply. One charge of $597.
1.7 mg weekly
Maintenance
$249/mo
1 vial (25 mg), a 3-month supply. One charge of $747.
2.4 mg weekly
Maintenance
$249/mo
1 vial (25 mg), a 2-month supply. One charge of $498.

Your dose and price step up together as Dr. Rachel advances your protocol. She will discuss any change with you first.

How the price works
Unit size
25 mg vial
Prescribed dose
2.4 mg weekly
Frequency
weekly
How long one unit lasts
about 10 weeks per vial
vials per year
4 vials over 12 months
Per month
$179
Per dose
about $41
What’s included
  • Clinician review by Dr. Rachel Deutsch, DNP
    She reviews your case and prescribes the protocol. Every 4th refill returns to her for a scheduled check-in, and she can adjust that cadence based on your specific care. Not a bot, not a checkbox.
  • Compounding by a licensed US pharmacy
    503A partnership. Every batch traceable, every ingredient sourced under FDA oversight.
  • Temperature-controlled shipping when required
    Temperature-controlled packaging for injectables that need it. Ground shipping for orals and topicals.
  • Unlimited messaging with your care team
    Ask Rachel anything, any time. Dr. Rachel typically replies within one business day.
  • No charge until Rachel approves your order
    Your card is authorized at checkout, captured only when Rachel signs off. If she declines, nothing is charged.
Reviewed by Dr. Rachel Deutsch, DNP · US compounding pharmacy · Cancel anytime

* Statements have not been evaluated by the FDA. Semaglutide is prescribed by a licensed clinician based on individual clinical review. Not intended to diagnose, treat, cure, or prevent any disease. See your prescribing clinician for personalized guidance.

GLP-1 weight management, prescribed personally., Tides