The CoQ10 your statin depletes.^*

CoQ10 is the molecule every mitochondrion needs to convert food into ATP. Decline maps directly to the fatigue most adults attribute to aging.

Foundational

CoQ10

Ubiquinol

Tides · Clinician-Prescribed

What it is

Coenzyme Q10 (ubiquinone) — a fat-soluble compound essential to the electron transport chain inside every mitochondrion. Tides uses the injectable, prescription-strength form, not the oral supplement that absorbs poorly.

Primary benefit

Physical stamina, cardiovascular support, and a quieter baseline fatigue — particularly meaningful for patients on statins.

Mechanism

Refills mitochondrial CoQ10 pools so cells can convert nutrients into ATP at the rate they did when you were younger.

Who it's for

Adults on statin medications (which deplete CoQ10), patients with cardiovascular focus, and the longevity-stack crowd targeting mitochondrial health.

Read the full science

What Tides prescribesCoQ10Intramuscular delivery. Bypasses absorption ceiling. Therapeutic dose.

What's on the shelf in pharmaciesOral CoQ10 supplementsFat-dependent absorption. Dose-dependent uptake. Plateaus quickly.

What it does

Physical energy and stamina
The fatigue that arrives in the late 30s is usually mitochondrial. Restoring CoQ10 lifts the floor on physical output without acting like a stimulant.
Cardiovascular function
The heart has the highest mitochondrial density in the body. Clinical evidence supports CoQ10 in heart failure, post-MI recovery, and statin-related fatigue.
Statin-induced fatigue
Statins block the same biosynthetic pathway that produces CoQ10. Patients on statins commonly feel the difference within weeks of supplementation.
Migraine prevention
Multiple randomized trials show meaningful reduction in migraine frequency and severity. Often the first low-risk intervention worth trying.

How it works

CoQ10 (ubiquinol form) is a fat-soluble compound essential to the electron transport chain in every mitochondrion. Endogenous production declines after age 30, and statin medications further block its synthesis. Injectable delivery achieves blood levels oral supplements struggle to reach, which matters most when the goal is restoring fatigue thresholds rather than maintaining baseline.